Last night, Greensky Bluegrass hit Washington, DC for the first of their three nights at the 9:30 Club with friends Fruition. Greensky certainly rose to the occasion, putting together a solid show that inevitably will get fans stoked for the next two nights. In honor of Groundhog’s Day and in keeping with tradition, the band opened with “Groundhog.”Moving into the second set, the band was fired up, busting out “Cold Feet” to kick things off after set break for a stacked second set. After “Can’t Stop Now,” which featured quotes from Martin Luther King Jr.’s “I Have A Dream Speech,” the band began a cover of The Wood Brother’s “Luckiest Man.” For this track, Mimi Naja and Jay Cobb Anderson of supporting band Fruition joined Greensky. Following this sit-in, Greensky busted out “Freeborn Man,” during which Michael Bont threw down an inspiring solo.The rest of the second set was a non-stop scorcher, which saw Mimi Naja return for “Worried About The Weather.” You can watch video of last night’s “Freeborn Man” below, courtesy of Troy Laur.You can see the setlist, courtesy of Lucas White, as well as a full gallery from Mark Raker below.Setlist: Greensky Bluegrass | 9:30 Club | Washington, DC | 2/2/2017Set 1: Groundhog (1) 》 Handle with Care, Depot Bay, Take Cover, Better Off, Reverend, Crying Holy Unto the Lord, While Waiting, All FourSet 2: Cold Feet, In Control > Can’t Stop Now (2), Luckiest Man (3)(4), Freeborn Man (5)(6) 》The Four, Wheel Hoss, Forget Everything (7), Worried About the Weather (8) 》Foxy Lady 》Worried about the WeatherE: Fixin’ to Ruin (9)Notes: (1) “Reuben’s Train” teases, (2) Martin Luther King “Dream” speech quotes, (3) With Jay Cobb Anderson and Mimi Naja, (4) “Say It Ain’t So” quotes, (5) Anders vocal mirror guitar during opening, (6) “Paint It Black” teases, (7) With Mimi Naja on harmony vocals, (8) “Dark Star’ teases, (9) Kevin Gregory on vibraslap Load remaining images
Researchers at Harvard-affiliated Brigham and Women’s Hospital (BWH) studying mesenchymal stem cells (MSCs) — a cell type useful in treating immune-related diseases — have uncovered a way to enhance and prolong the cells’ therapeutic effects in a preclinical model of Type 1 diabetes.The research team, led by Harvard Medical School (HMS) Professor Robert Sackstein of BWH’s Departments of Dermatology and of Medicine and HMS Associate Professor Reza Abdi of BWH’s Department of Medicine and Transplantation Research Center, reports its results this week in the journal Stem Cells.In Type 1 diabetes, the body’s immune cells obliterate pancreatic islets, where insulin is produced. MSCs are a type of adult stem cell with potent immune-suppressing and anti-inflammatory effects. In preclinical trials using diabetic-prone mice (non-obese diabetic mice), researchers had previously found that intravenous administration of MSCs could dampen pancreatic injury by reducing the levels of sugar in the mice’s bloodstreams without insulin administration, but these effects were modest and temporary.Sackstein and his team hypothesized that if more MSCs could be forced to populate inside the pancreatic islets, more islets could be spared from immune destruction, yielding a more complete reversal of diabetes.MSCs normally lack a key cell surface adhesion molecule called HCELL, which mediates the homing of cells in the bloodstream to sites of tissue inflammation. The injection of MSCs directly into pancreatic islets is not feasible because the pancreas is fragile and releases highly toxic enzymes when manipulated. To get intravenously administered MSCs to the sites of the immune attack, the research team engineered the HCELL homing molecule to steer them toward the inflamed pancreatic islets.The team found that administering HCELL-bearing MSCs into diabetic mice caused the MSCs to lodge in the islets. The result was durable normalization of blood sugar levels, eliminating the need for insulin administration — a sustained reversal of diabetesSackstein, co-corresponding author of the study, concluded that while further studies of the effects of MSCs are warranted, the preclinical study represents an important step in the potential use of mesenchymal stem cells in the treatment of Type 1 diabetes and other immune-related diseases.
May 14, 2009WHO: No decision yet on H1N1 vaccine productionExperts convened by the World Health Organization (WHO) today made no decision on recommending mass production of a vaccine for the novel H1N1 virus, and how soon such a recommendation might come is uncertain, said Dr. Keiji Fukuda of the WHO. “No big decision, no pronouncements,” he told reporters. Calling the issue “enormously complicated,” he said a series of additional meetings will be needed. “It’s not possible to say a decision will be made by this [a specific] date,” he said.[May 14 WHO briefing audio file]Global novel influenza total tops 6,000The global number of novel H1N1 influenza cases reached 6,497 in 33 countries, the World Health Organization (WHO) reported today. The count includes 2,446 cases and 60 deaths in Mexico, 3,352 cases and 3 deaths in the United States as of yesterday, and 8 cases and 1 death in Costa Rica. Other countries with more than a dozen cases include Spain (100), the United Kingdom (71), Panama (29), and France (14).[WHO update 28]US novel flu cases pass 4,000Today the US tally of confirmed H1N1 cases grew to 4,298, of which 3 were fatal, in 47 states, the Centers for Disease Control and Prevention (CDC) reported. North Dakota and Arkansas, with one case each, were added to the list of affected states today.[Current CDC numbers]WHO shortens upcoming World Health AssemblyThe WHO today announced a shortened schedule for the upcoming World Health Assembly. The WHO had been considering the move to allow more time for health ministers to address H1N1 issues in their own countries. The WHA starting date is still May 18, but the meeting will end on May 22 instead of May 27. The agenda includes pandemic preparedness, influenza virus sharing, the International Health Regulations, and WHO budgets and administration.[May 14 WHO statement]Poll finds low demand for potential new flu vaccineA Zogby/University of Texas poll found that only 30% of respondents would get a vaccine for the novel H1N1 outbreak if one was available. Only 18% saw the outbreak as a severe threat, and 96% said they have not curbed their visits to restaurants or malls. Forty percent were confident in the government’s ability to manage the outbreak. Only 36% of respondents said they received a flu immunization for the 2008-09 season. The online poll surveyed 1,442 adults between May 4 and 6.[May 13 Zogby press release]NIH renews support for Baylor flu vaccine researchThe Baylor Institute for Immunology Research recently announced that the National Institutes of Health renewed its grant, worth $14 million over the next 5 years, to design new influenza vaccines. The work involves molecules that target the immune system’s dendritic cells. The institute applied for a grant supplement to make a vaccine against the novel H1N1 virus.[May 11 Baylor press release]
Robert P. Crowell, age 76 of Batesville, died Saturday, November 11, 2017 at Margaret Mary Health. Born February 7, 1941 in Chicago, Illinois, he is the son of Ruth (Nee: Steele) and Cecil Crowell. He married Linda Pactwa August 3, 1963 at St. Paul’s Church in Hammond, Indiana. Bob taught Industrial Arts and Drafting for 33 years before retiring. His first two years were at Sunman and his last 31 in Batesville. He enjoyed working with young people. He started the Coonhunters Junior Conservation Club, worked on many projects with students through the Rural Alliance for the Arts, coached the high school track and cross country teams for 10 years and had a program similar to Junior Achievement in which his students would create a business, manufacture a product and sell it to the public.Other interests included being a member of the Tri-County Harmonizers Barbara Shop Quartet, a former member of the Coonhunters small bore rifle team and re-furbishing and re-finishing antiques with Linda. They also owned and operated the Safari Camp Ground for 16 years. Bob collect gas memorabilia and loved to collect and restore antique steam and gas engine tractors. A member of the Pioneer Engineers Club of Rushville, he had articles published in 23 magazines on the subject.Another love of Bob’s was cars. Over the years he owned several collectable cars and was a member of the Corvair Club of Indianapolis, the Corvair Club of Cincinnati, Vintage T-Bird Club of Indianapolis, the Ford Model T Club of America, the Ford Model T Club of Indianapolis, and the Hoosier Hills Car Club.Bob is survived by his wife Linda; daughter Patricia Crowell-Gentles of Lambertville, New Jersey; brother James Crowell of Valparaiso, Indiana as well as numerous nieces and nephews. He is preceded in death by his parents. Visitation is Wednesday, November 15th, from 4 – 7 p.m. at the Weigel Funeral Home. Funeral services are 10 a.m. Thursday, November 16th, at the Batesville United Methodist Church with Rev. Chris Renick and Rev. Charles Flory officiating. Burial will follow in the church cemetery. The family requests memorials to Safe Passage.
Matt Chapman had just executed a Matrix-like side-belly slide, evading White Sox … Oakland Coliseum’s vast foul territory has its pits and perks.Sunday afternoon, the A’s home turf helped deliver the team a 3-2, walk-off win to seal a series sweep of the Chicago White Sox.Here are three takeaways.Unfavorable challenges and redemption inningsThe moment crew chief Larry Vanover took off his headset and pumped his fist out, it looked like the A’s hot streak would trip over a blip.